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  1. Suzetrigine - Wikipedia

    Suzetrigine, sold under the brand name Journavx, is an oral medication used for moderate to severe acute pain management in adults. [1][2] It is a small-molecule non- opioid analgesic that works as a …

  2. FDA Approves Novel Non-Opioid Treatment for Moderate to Severe …

    Jan 30, 2025 · Today, the U.S. Food and Drug Administration approved Journavx (suzetrigine) 50 milligram oral tablets, a first-in-class non-opioid analgesic, to treat moderate to severe acute pain in …

  3. Journavx: Uses, Dosage, Side Effects, Warnings - Drugs.com

    Feb 3, 2025 · Journavx (suzetrigine) is a new non-opioid pain-relieving tablet used to treat short-term (acute) moderate to severe pain. Journavx is a sodium channel blocker that relieves pain by blocking …

  4. JOURNAVX® (suzetrigine) for Moderate-to-Severe Acute Pain

    JOURNAVX is a prescription medicine used to treat adults with moderate-to-severe short-term (acute) pain. It is not known if JOURNAVX is safe and effective in children. Do not take JOURNAVX if you …

  5. Suzetrigine (oral route) - Side effects & dosage - Mayo Clinic

    Nov 1, 2025 · Description Suzetrigine is used to treat moderate to severe short-term pain. This medicine is available only with your doctor's prescription. This product is available in the following dosage …

  6. Suzetrigine is the first novel mechanism of action analgesic approved in decades. In acute, post-operative pain it has a modest reduction in pain, with a small effect size that is numerically better …

  7. Suzetrigine: MedlinePlus Drug Information

    Why is this medication prescribed? Suzetrigine is used as a short-term treatment to relieve moderate to severe pain. Suzetrigine is in a class of medications called sodium channel blockers. It works by …

  8. Pharmacology and Mechanism of Action of Suzetrigine, a Potent and ...

    Suzetrigine (VX-548) is a potent and selective inhibitor of Na V 1.8, which has demonstrated clinical efficacy and safety in multiple acute pain studies.

  9. More Data on Suzetrigine, a Novel Nonopioid Pain Medication

    May 1, 2025 · Suzetrigine, a selective sodium-channel blocker that inhibits nociceptive pain signaling in peripheral nerves, was approved by the FDA in January 2025 “for the treatment of moderate to …

  10. Suzetrigine (Journavx), an Opioid Alternative for Pain - GoodRx

    Jan 31, 2025 · Suzetrigine is a non-opioid medication that treats moderate-to-severe pain in adults. It’s meant for acute (short-term) use, not chronic use. It’s a 50 mg oral tablet that you can take twice …