The ability to precisely edit the genomes of bacteria has long been a goal of microbiologists. Such technology would enable ...

New research shows that the nuclease domain of the E. coli RecBCD helicase plays a key role in regulating DNA binding and the extent of base pair melting during double-strand break repair. Deleting ...

We have gone further than ever before in creating life that is unlike anything that has evolved naturally. The genome of an Escherichia coli bacterium has been redesigned on a computer to use just 57 ...

A multi-lab team led by Gladstone Institutes has successfully adapted retron-based genome editing—previously limited to E. coli—for use in 14 additional bacterial species across three major branches ...