Metabolic profiling using Seahorse analysis showed that CCR5 inhibition reduced oxygen consumption rate (OCR) in a dose-dependent manner, consistent with modulation of glycolytic and metabolic ...

Advances in tissue-based technology in the past few years have created unprecedented opportunities to identify biomarkers of disease processes, especially within oncology by using multi-omics ...

Existing oncology therapeutics are either so specific they can target only part of a tumor, or so generalized they kill healthy tissue. A new “Tumor Activated Therapy™” in development at the small ...

Srinagar: The Department of Biochemistry, University of Kashmir (KU), is set to host the 45th Annual Meeting of the Indian ...

The inflammatory tumor microenvironment (TME) is a complex network of cancer, immune, and stromal cells interacting through cytokines and growth factors to drive tumor growth, angiogenesis, and immune ...

lncRNAs and tumor microenvironment dynamics lncRNAs mediate the interactions between tumor cells and their surrounding microenvironment, influencing several aspects of tumor behavior. These ...

Despite substantial progress in cancer treatment, durable benefit is still frequently limited by the ability of tumors to adapt under therapeutic pressure.

Tumors driven by cancer-driving KRAS mutations are often susceptible to ferroptosis, a type of cell death that can be ...

In the field of neuro-oncology, the dual topics of cellular metabolism and the tumor microenvironment (TME) have gained ...