Using a tiny, spherical glass lens sandwiched between two brass plates, the 17th-century Dutch microscopist Antonie van Leeuwenhoek was the first to officially describe red blood cells and sperm cells ...

Microscopy continues to transform the life sciences. Here are five recent breakthroughs made possible by the technique.

Characterizing cells based on their surface proteins is a key concept in cell biology research that extends substantially into diagnostics and therapeutics. Notable examples include reporting the ...

Cell surface receptors, such as the G-protein coupled receptor (GPCR) and receptor tyrosine kinase (RTK), play central roles signalling pathways. Due to their central role in regulating a wide range ...

Even those who maintain that super-resolution microscopy is a powerful tool of biological discovery have admitted that it may have a bit of an image problem. For example, in a recent review, several ...