In a first for the genetic toolset known as CRISPR, a recently discovered protein has been found to act as a kind of multipurpose self-destruct system for bacteria, capable of degrading ...

In the CRISPR toolkit, Cas12a2 is like a Swiss Army Knife—one tool that can do multiple things. The nuclease performs RNA-guided, sequence-nonspecific degradation of single-stranded RNA, ...

Researchers from Carnegie Mellon University have discovered a way to target RNA that could lead to new treatment options for myotonic dystrophy type 1 (DM1), the most common adult-onset form of ...

Share on Facebook (opens in a new window) Share on X (opens in a new window) Share on Reddit (opens in a new window) Share on Hacker News (opens in a new window) Share on Flipboard (opens in a new ...

Researchers identify a shared RNA-protein interaction that could lead to broad-spectrum antiviral treatments for enteroviruses ...

RNA Timeline: A History in Hybridization and Structure Alexander Rich and David Davies discover the double-stranded RNA helix and show that polyribo U and polyribo A hybridize spontaneously.6 Ben Hall ...

In 1957, just four years after Francis Crick and other scientists solved the riddle of DNA’s structure—the now famous double helix—Crick laid out what he called the “central dogma” of molecular ...

It might enable inexpensive, highly sensitive at-home diagnostic tests for COVID-19, influenza, Ebola and more. In this illustration based on cryo-electron microscope images, a Cas12a2 protein unzips ...