This work was supported by grants from the National Natural Science Foundation of China (Nos. 82471497, 82311530117, and ...

Pyroptosis is a form of cell death that relies on gasdermins-mediated formation pores in the plasma membrane, which subsequently promotes inflammation by releasing immunogenic cellular contents. The ...

TBI remains a major cause of death and long-term neurological disability worldwide, yet effective treatments for secondary ...

Kangbaida (Sichuan) Biotechnology Co. Ltd. has disclosed pyroptosis and NLRP3 inflammasome inhibitors reported to be useful for the treatment of cancer, type 1 diabetes, gout, inflammatory disorders, ...

Neurogenic bladder is a disease involving inflammation and fibrosis of the bladder. Fibrosis has been linked to the type of programmed cell death known as pyroptosis, which in turn has been linked to ...

Neuroinflammation has emerged as a pivotal area of study over recent decades, propelled by its critical involvement in both ...