For the millions of people living with genetic diseases like muscular dystrophy and inherited liver disorders, one of the ...

Scientists are laying the groundwork for treating one of the most common genetic conditions in humans. Research out today ...

Scientists have taken an important step toward a gene therapy that could one day turn off the extra genetic material that ...

A compact Cas12f nuclease shows high editing efficiency in human cells, with structural insights enabling an engineered variant potentially suited for future AAV‑compatible delivery.

By using CRISPR/Cas9 to engineer cells from healthy donors, AVC-203 is designed to circumvent graft-versus-host disease and host-mediated rejection.

The last time The Lancet Microbe featured an Editorial on CRISPR was in November 2020, to mark that year’s Nobel Prize in Chemistry, jointly awarded to Emmanuelle Charpentier and Jennifer A Doudna for ...

CRISPR functions as a programmable genetic memory system derived from bacterial immune defenses against viral infections. Guide RNA allows for rapid multiplexed targeting compared to older ...

The CRISPR-Cas gene-editing system has long been the focus of research as a promising tool in genome editing. However, the ...