Researchers at VIB and KU Leuven have identified a molecular process that allows motor neurons to maintain protein production ...

Mutations in the microtubule-binding protein tau cause the protein to aggregate in neurodegenerative diseases such as some forms of frontotemporal dementia—but many conditions evince tau tangles in ...

A team of researchers used stem cell technology to generate motor neurons from ALS patients carrying mutations in FUS. They found disturbed axonal transport in these motor neurons, but also identified ...

Reactivating damaged motoneurons Thomas Herrmannsdörfer (left) and Richard Funk are investigating the therapeutic effect of magnetic fields on impaired motoneurons. (Courtesy: HZDR/Amac Garbe) ...

Hereditary axonal peripheral neuropathies comprise a genetically heterogeneous group of disorders that are clinically subsumed under the name of Charcot–Marie–Tooth (CMT) disease type 2 (CMT2).

Seeking students to contribute to research exploring motor-disease protein complexes and their role in intracellular transport, as they relate to disease initiation and the aging process, and the ...

Researchers have identified KIF5A as a new gene associated with the development of amyotrophic lateral sclerosis (ALS). The discovery further implicates the role of cytoskeletal defects in the axon as ...

Early in the course of Alzheimer disease, blockages in axonal traffic lead to sick axons swollen with the jumbled pile-up of traffic components. The blockages precede overt amyloid pathology in AD ...