The inappropriate expression of TGFα in growth arrest contributes to malignant progression in human colon carcinoma cells. Early stage, non-progressed colon tumor cells show a down-regulation of TGFα ...
Many biological signaling pathways involve autocrine ligand–receptor loops; misregulation of these signaling loops can contribute to cancer phenotypes. Here we present an algorithm for detecting such ...
Misregulation of autocrine signalling loops may contribute to cancer phenotypes. In November Nature Genetics, Thomas Graeber and David Eisenberg of the Howard Hughes Medical Institute and the ...
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